Ranking Stanford
Cuatro investigadores del IMSE, entre el 2% de los mejores del mundo

La Universidad de Stanford, en California, ha publicado la lista 'Ranking of the World Scientists: World´s Top 2% Scientists', que recoge a profesionales de la investigación cuyos trabajos han sido más citados durante su carrera profesional hasta 2019. En dicha lista aparecen los investigadores del IMSE Bernabé Linares, Ángel Rodríguez, Teresa Serrano y José Manuel de la Rosa.


Chips, un inventario sin stock
Chips, un inventario sin stock

Entrevista al profesor José Manuel de la Rosa para el programa 'Puerta al Presente' de RNE Radio 5, sobre el desabastecimiento existente en el mercado de semiconductores.


Desabastecimiento de chips
Desabastecimiento de chips: un problema y una oportunidad

Artículo del profesor José Manuel de la Rosa en la plataforma 'The Conversation', acerca de los serios problemas de suministro que la creciente demanda de chips está provocando en diversos sectores de la industria.


La Noche Europea de l@s Investigador@s
La Noche Europea de l@s Investigador@s 2021

El IMSE-CNM en la Noche Europea de l@s investigador@s 2021. Los investigadores Erica Tena, Francisco Eugenio Potestad y José Miguel Mora presentaron la actividad '¿Te apetece una partida? Videojuego «Frogger» reutilizando placas programables para diseño microelectrónico'.


Tesis Doctoral
Defensa de Tesis Doctoral

Impacto de la variabilidad dependiente del tiempo en circuitos integrados en tecnologías nanométricas: modelado, simulación y caracterización experimental.
Pablo Martín Lloret  ·  17 Septiembre 2021

Del chip a la sociedad digital
Del chip a la sociedad digital

Artículo del profesor José Manuel de la Rosa en la plataforma 'The Conversation', acerca del impacto que en nuestras sociedades está produciendo el desarrollo de la microelectrónica.



Empleo en el IMSE

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Formación en el IMSE

- Doctorado
- Máster
- Grados
- Trabajos Fin de Grado
- Prácticas en Empresa


Publicaciones recientes

The role of intra-clutch variation of magpie clutches in foreign egg rejection depends on the egg trait considered
M. Molina-Morales, J. Gómez, G. Liñan, M. Precioso, J.G. Martinez and J.M. Avilés
Journal Paper · Frontiers in Ecology and Evolution, first online, 2021
FRONTIERS    ISSN: 2296-701X

The existence of a coevolutionary process between avian brood parasites and their hosts predicts a lower intra-clutch variation in egg appearance of host eggs among rejecters as this would favour egg discrimination of parasite eggs by hosts once parasitic egg mimicry had evolved. So far empirical tests of this prediction have ignored the fact that different aspects of host egg phenotypes may differ in the relative role of environmental versus genetic determination, and hence that the role of intra-clutch variation in egg rejection within a population cannot be invariant. Here, we estimated whether the intra-clutch variation in several aspects of host eggshell features is consistently associated to rejection of parasitic foreign eggs across years in a magpie host population parasitized by great spotted cuckoos. We innovatively estimated spottiness by means of the fractal dimension of eggs, which considers the homogeneity of spot pattern complexity in eggshells. Our results show that low intra-clutch variation in the blue-green coloration at the middle area of the eggs associated with a high chance of rejection, but only in one of the three years we conducted the study. In addition, females that rejected foreign eggs presented more homogenous spot patterns in their clutches as estimated by their fractal dimension than females that accepted experimental eggs, independently of the year of study. Finally, intra-clutch variation in egg volume of host eggs was not associated to rejection. Analyses at the individual level revealed that the relative role of genetic versus environmental factors determination egg phenotype would be feature-specific in magpies, females having a characteristic spottiness, but not colour or volume, pattern. Our work stresses the importance of considering a holistic approach including several aspects of variation in host egg phenotype (size, colour, and homogeneity of spot pattern), as some aspects might be more susceptible to selection through egg rejection than others, presumably because they are less influenced by variation in the environmental conditions. Moreover, our study highlights the importance of replication in studies on the adaptive value of host traits in egg rejection.

Reducing the Nonlinearity and Harmonic Distortion in FD-SOI CMOS Current-Starved Inverters and VCROs
P.I. Okorie, J. Ahmadi-Farsani and la Rosa
Journal Paper · AEU - International Journal of Electronics and Communications, first online, 2021
ELSEVIER    ISSN: 1434-8411
resumen      doi      

This paper demonstrates experimentally how to reduce the nonlinearity of some analog and mixed-signal circuits by using the enhanced body effect provided by Fully-Depleted Silicon on Insulator (FD-SOI) CMOS technology. A current-starved CMOS inverter and a Voltage-Controlled Ring Oscillator (VCRO) are considered as case studies. The inverter is configured as a simple amplifier stage in which the harmonic distortion can be reduced and even removed by the combined action of the control voltages applied at the gate and bulk terminals of the current-source transistors. This current-starved inverter is used as the basic building block of a VCRO, where a more linear voltage-to-frequency characteristic can be achieved if the bulk terminal is used as the control voltage of the oscillator. The circuits under study have been designed and fabricated in a 28-nm FD-SOI technology and experimental results are shown to validate the presented approach.

Thermography for the differential diagnosis of vascular malformations
J.A. Leñero-Bardallo, C. Serrano, B. Acha, J.A. Pérez-Carrasco and J. Bernabeu-Wittel
Journal Paper · Clinical and Experimental Dermatology, vol. 46, no. 2, pp 314-318, 2021
JOHN WILEY & SONS    ISSN: 0307-6938
resumen      doi      pdf

Vascular malformations classification may pose a diagnostic challenge for physicians. In the early stages, they are diagnosed clinically mainly by visual inspection. For a deeper analysis, Doppler ultrasonography is the preferred technique to determine the haemodynamic behaviour of the anomaly. However, this imaging method is not always available and it requires trained operators to acquire and interpret the images. There is a lack of portable and user-friendly systems that may help physicians in the assessment of vascular malformations. We propose a new diagnostic procedure, more affordable and easier to use, based on a portable thermal camera. This technique provides information about temperature, which has been found to be correlated with the flow rate of the lesion. In our study, > 60 vascular malformations of previously diagnosed patients were analysed with a thermal camera to classify them into low-flow and high-flow malformations. The value was 1 for both sensitivity and specificity of this technique.

Baseline Features Extraction from Microelectrode Array Recordings in an in vitro model of Acute Seizures using Digital Signal Processing for Electronic Implementation
G. Galeote-Checa, G. Panuccio, B. Linares-Barranco and T. Serrano-Gotarredona
Conference · IEEE International Conference on Omni-Layer Intelligent Systems COINS 2021

Latest advances in CMOS technology, neuromorphic computing and flexible electronics are leading the way to a new era of brain implantable devices that promise to provide innovative and more effective treatments for brain disorders. Real-time signal detection and classification, as well as anticipation of brain electrical activity are yet under development. Microelectrode arrays (MEA) arise as a promising technology enabling detection of local fieldpotentials from multiple locations and permitting the acquisition of more information on brain network electrical activity than conventional electrophysiology techniques. However, whereas most of the electrophysiological studies addressing brain activity have focused on events/patterns analysis, no one has so far addressed the features that might be hidden within the signal baseline. Such features might be particularly relevant in the context of epilepsy, as the signal baseline may carry relevant information for seizure prediction. Here, we present a preliminary processing and analysis of signal baseline acquired through MEA in an in vitro model of limbic seizures. The signal conditioning was implemented using an infinite impulse response (IIR) digital filter. After signal preprocessing, we applied an averaging method to 16 baseline sections to find common patterns and to study the frequency spectrum of this type of signal. We have found signal components between 0.5-2 Hz and peaks at 350, 390 and 650 Hz. In addition, the reconstruction of the averaged signal may provide insights into the main baseline wave patterns. These results might be a preliminary step to study the influence of those components on a biological basis. Based on these results, we propose a possible electronic architecture implementation of the signal processing method.


Investigación en el CSIC

Qué hacemos en el IMSE

El área de especialización del Instituto es el diseño de circuitos integrados analógicos y de señal mixta en tecnología CMOS, así como su uso en diferentes contextos de aplicación tales como dispositivos biomédicos, comunicaciones inalámbricas, conversión de datos, sensores de visión inteligentes, ciberseguridad, computación neuromórfica y tecnología espacial.

La plantilla del IMSE-CNM está formada por unas cien personas, entre personal científico y de apoyo, que participan en el avance del conocimiento, la generación de diseños de alto nivel científico-técnico y la transferencia de tecnología.


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